In comedy there is always the temptation to go for the easy jokes – but now, more than ever, comedians have to challenge themselves.

Here are two cutting-edge neuroscience technologies that may enable us to treat conditions like blindness, epilepsy and Alzheimer's.

What if the vision wasn't just to have politicians who are science literate, but actual scientists running the joint – would it be any better than it is now?

Despite decades of research, there is no reliable vaccine for malaria. Dr. Philip Eckhoff lays out the strategies and collaborations required to eradicate this disease and the half a million lives it takes each year.

We are what we are because of genes; we are who we are because of memes. Philosopher Daniel Dennett muses on an idea put forward by Richard Dawkins in 1976.

Jeffrey Sachs, from the Rust Belt himself, shares his thoughts on Trump's economic plans and shares some red flags to watch for as new policy proposals surface.

There's a trillion-dollar underground economy hiding in plain sight, says Steven Kotler, and it can be measured in dopamine.

Exterior mapping – like GPS maps – is part of daily life, but in the coming decades prepare to have your private, interior spaces mapped to assist with future technologies.

Scott Aukerman, the co-founder of 'Between Two Ferns', developed humor early on as a way disarm bullies. He knows from experience that, in comedy, your intentions really matter.

Mathematics professor Po-Shen Loh has created Expii, a free education tool that democratizes learning by turning your smartphone into a tutor.

Can't the U.S. be a little more like Scandinavia in its ethos? Fixing inequality in America will take more than economic reform, it will also need a cultural shift.

Time is this wild fourth dimension in nature, says Bill Nye. We depend on its neat measurements for survival – but subjectively it continues to elude us.

The human mind is like a Turing machine, says Daniel Dennett. It's made up of unthinking cogs – but when combined in the right order, their motion gives rise to consciousness.

Astro Teller's innovation tip? Fail fast. Here's how he cultivates and rewards intellectually honest failures, and helps his team get comfortable with the idea.

We cannot rule out the possibility that a superintelligence will do some very bad things, says AGI expert Ben Goertzel. But we can't stop the research now – even if we wanted to.

Here's one use for all that harvested personal data that you might not object to. Algorithms and big data are no longer just for profit; they can bring us self-awareness and growth.

Nothing reflects the complex mood of our era like gaming, says Nato Thompson, where the establishment has worked its way into the anti-establishment ethos.

Evolutionary biologists generally agree that humans evolved from a bacteria-like ancestor, rather than a viral one. But what if we're chemically connected?

One day this century, a robot of super-human intelligence will offer you the chance to upgrade your mind, says AGI expert Ben Goertzel. Will you take it?

When you take off a virtual reality headset, you don't remember seeing things, you recall experiencing them, says Kevin Kelly. VR will create a world of amazing opportunity – for us and for advertisers.